Structural Biology

26 MG 718
2 graduate credits

Co-Course Directors: Drs. Paul Rosevear and Mark Rance

This course will cover structural techniques used to determine protein structure, dynamics and enzyme mechanisms. Particular emphasis will be placed on solution NMR techniques to problems in protein structure and enzyme mechanism. The course will consist of both lectures and a review of pertinent literature articles. Topics that will be covered include NMR theory, practical aspect of biological NMR, the use of structural techniques in understanding HIV proteins, structural studies of muscle proteins, as well as mechanistic studies of ribonucleases and phosphoryl transfer enzymes. To be offered Spring Quarter each year.